Ligand Id: 185
Ligand name MDL-100,907

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 41.93
Molecular weight 373.21
XLogP 4.11
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands Radio analogues
References
1. Knight, A. R., Misra, A., Quirk, K., Benwell, K., Revell, D., Kennett, G. and Bickerdike, M. (2004)
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Naunyn Schmiedebergs Arch Pharmacol, 370: 114-123. [PMID:15322733]
2. Lopez-Gimenez, J. F., Villazon, M., Brea, J., Loza, M. I., Palacios, J. M., Mengod, G. and Vilaro, M. T. (2001)
Multiple conformations of native and recombinant human 5-hydroxytryptamine(2a) receptors are labeled by agonists and discriminated by antagonists.
Mol Pharmacol, 60: 690-699. [PMID:11562430]
3. Reavill, C., Kettle, A., Holland, V., Riley, G. and Blackburn, T. P. (1999)
Attenuation of haloperidol-induced catalepsy by a 5-HT2C receptor antagonist.
Br J Pharmacol, 126: 572-574. [PMID:10188965]