[3H]apafant

Ligand id: 1859

Name: [3H]apafant    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 100.85
Molecular weight 455.12
XLogP 3.46
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Aoki Y, Nakamura M, Kodama H, Matsumoto T, Shimizu T, Noma M. (1995)
A radioreceptor binding assay for platelet-activating factor (PAF) using membranes from CHO cells expressing human PAF receptor.
J Immunol Methods186: 225-231. [PMID:7594622]
2. Fukunaga K, Ishii S, Asano K, Yokomizo T, Shiomi T, Shimizu T, Yamaguchi K. (2001)
Single nucleotide polymorphism of human platelet-activating factor receptor impairs G-protein activation.
J Biol Chem276: 43025-43030. [PMID:11560941]
3. Nakamura M, Honda Z, Izumi T, Sakanaka C, Mutoh H, Minami M, Bito H, Seyama Y, Matsumoto T, Noma M et al.. (1991)
Molecular cloning and expression of platelet-activating factor receptor from human leukocytes.
J. Biol. Chem.266 (30): 20400-5. [PMID:1657923]