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Synonyms: [Arg1,Trp7,9,Leu11]substance P | [D-Arg1,D-Trp7,9,Leu11]-Substance P
Compound class:
Peptide or derivative
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
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1. Folkers K, Feng DM, Asano N, Håkanson R, Weisenfeld-Hallin Z, Leander S. (1990)
Spantide II, an effective tachykinin antagonist having high potency and negligible neurotoxicity. Proc Natl Acad Sci USA, 87 (12): 4833-5. [PMID:1693780] |
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2. Håkanson R, Leander S, Asano N, Feng DM, Folkers K. (1990)
Spantide II, a novel tachykinin antagonist having high potency and low histamine-releasing effect. Regul Pept, 31 (1): 75-82. [PMID:1702895] |
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3. Yachnis AT, Crawley JN, Jensen RT, McGrane MM, Moody TW. (1984)
The antagonism of bombesin in the CNS by substance P analogues. Life Sci, 35 (19): 1963-9. [PMID:6208451] |
