ondansetron

Ligand id: 2290

Name: ondansetron

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 39.82
Molecular weight 293.15
XLogP 2.92
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Brady CA, Stanford IM, Ali I, Lin L, Williams JM, Dubin AE, Hope AG, Barnes NM. (2001)
Pharmacological comparison of human homomeric 5-HT3A receptors versus heteromeric 5-HT3A/3B receptors.
Neuropharmacology41 (2): 282-4. [PMID:11489465]
2. Hope AG, Peters JA, Brown AM, Lambert JJ, Blackburn TP. (1996)
Characterization of a human 5-hydroxytryptamine3 receptor type A (h5-HT3R-AS) subunit stably expressed in HEK 293 cells.
Br. J. Pharmacol.118 (5): 1237-45. [PMID:8818349]
3. Miyake A, Mochizuki S, Takemoto Y, Akuzawa S. (1995)
Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among species.
Mol. Pharmacol.48 (3): 407-16. [PMID:7565620]