Ligand Id: 2290
Ligand name ondansetron

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 39.82
Molecular weight 293.15
XLogP 2.92
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands
References
1. Miyake, A; Mochizuki, S; Takemoto, Y; Akuzawa, S. (1995)
Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among species.
Mol. Pharmacol., 48 (3): 407-16. [PMID:7565620]
2. Brady, CA; Stanford, IM; Ali, I; Lin, L; Williams, JM; Dubin, AE; Hope, AG; Barnes, NM. (2001)
Pharmacological comparison of human homomeric 5-HT3A receptors versus heteromeric 5-HT3A/3B receptors.
Neuropharmacology, 41 (2): 282-4. [PMID:11489465]
3. Hope, AG; Peters, JA; Brown, AM; Lambert, JJ; Blackburn, TP. (1996)
Characterization of a human 5-hydroxytryptamine3 receptor type A (h5-HT3R-AS) subunit stably expressed in HEK 293 cells.
Br. J. Pharmacol., 118 (5): 1237-45. [PMID:8818349]