BIMU 1

Ligand id: 233

Name: BIMU 1

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 55.89
Molecular weight 328.19
XLogP 2.41
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Blondel O, Gastineau M, Dahmoune Y, Langlois M, Fischmeister R. (1998)
Cloning, expression and pharmacology of four human 5-hydroxytryptamine 4 receptor isoforms produced by alternative splicing in the carboxyl terminus.
J. Neurochem.70: 2252-2261. [PMID:9603189]
2. Claeysen S, Sebben M, Journot L, Bockaert J, Dumuis A. (1996)
Cloning, expression and pharmacology of the mouse 5-HT(4L) receptor.
FEBS Lett398: 19-25. [PMID:8946946]
3. Mialet J, Berque-Bestel I, Eftekhari P, Gastineau M, Giner M, Dahmoune Y, Donzeau-Gouge P, Hoebeke J, Langlois M, Sicsic S, Fischmeister R, Lezoualc'h F. (2000)
Isolation of the serotoninergic 5-HT4(e) receptor from human heart and comparative analysis of its pharmacological profile in C6-glial and CHO cell lines.
Br J Pharmacol129: 771-781. [PMID:10683202]
4. Mialet J, Berque-Bestel I, Sicsic S, Langlois M, Fischmeister R, Lezoualc'h F. (2000)
Pharmacological characterization of the human 5-HT(4(d)) receptor splice variant stably expressed in Chinese hamster ovary cells.
Br J Pharmacol131: 827-835. [PMID:11030734]