bepridil

Ligand id: 2337

Name: bepridil

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 10
Topological polar surface area 15.71
Molecular weight 366.27
XLogP 6.8
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Honarnejad K, Daschner A, Giese A, Zall A, Schmidt B, Szybinska A, Kuznicki J, Herms J. (2013)
Development and implementation of a high-throughput compound screening assay for targeting disrupted ER calcium homeostasis in Alzheimer's disease.
PLoS ONE8 (11): e80645. [PMID:24260442]
2. Søgaard R, Ljungstrøm T, Pedersen KA, Olesen SP, Jensen BS. (2001)
KCNQ4 channels expressed in mammalian cells: functional characteristics and pharmacology.
Am. J. Physiol., Cell Physiol.280 (4): C859-66. [PMID:11245603]
3. Yang B, Gribkoff VK, Pan J, Damagnez V, Dworetzky SI, Boissard CG, Bhattacharjee A, Yan Y, Sigworth FJ, Kaczmarek LK. (2006)
Pharmacological activation and inhibition of Slack (Slo2.2) channels.
Neuropharmacology51 (4): 896-906. [PMID:16876206]