BIMU 8

Ligand id: 234

Name: BIMU 8

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 55.89
Molecular weight 342.21
XLogP 2.87
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Bonhaus DW, Berger J, Adham N, Branchek TA, Hsu SA, Loury DN, Leung E, Wong EH, Clark RD, Eglen RM. (1997)
[3H]RS 57639, a high affinity, selective 5-HT4 receptor partial agonist, specifically labels guinea-pig striatal and rat cloned (5-HT4S and 5-HT4L) receptors.
Neuropharmacology36: 671-679. [PMID:9225293]
2. Claeysen S, Faye P, Sebben M, Lemaire S, Bockaert J, Dumuis A. (1997)
Cloning and expression of human 5-HT4S receptors. Effect of receptor density on their coupling to adenylyl cyclase.
Neuroreport.8: 3189-3196. [PMID:9351641]
3. Claeysen S, Sebben M, Journot L, Bockaert J, Dumuis A. (1996)
Cloning, expression and pharmacology of the mouse 5-HT(4L) receptor.
FEBS Lett398: 19-25. [PMID:8946946]