Ligand Id: 2360
Ligand name [3H]strychnine

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 0
Topological polar surface area 32.78
Molecular weight 334.17
XLogP 1.73
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands Radio analogues
References
1. Grenningloh, G; Rienitz, A; Schmitt, B; Methfessel, C; Zensen, M; Beyreuther, K; Gundelfinger, ED; Betz, H. (1987)
The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors.
Nature, 328 (6127): 215-20. [PMID:3037383]
2. Vandenberg, RJ; Handford, CA; Schofield, PR. (1992)
Distinct agonist- and antagonist-binding sites on the glycine receptor.
Neuron, 9 (3): 491-6. [PMID:1326295]