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Synonyms: ω-CTx-MVIIC | SNX-230
Compound class:
Peptide or derivative
Comment: From Conus magus (Magus cone or Magician's cone snail)
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
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1. Hillyard DR, Monje VD, Mintz IM, Bean BP, Nadasdi L, Ramachandran J, Miljanich G, Azimi-Zoonooz A, McIntosh JM, Cruz LJ. (1992)
A new Conus peptide ligand for mammalian presynaptic Ca2+ channels. Neuron, 9 (1): 69-77. [PMID:1352986] |
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2. Lewis RJ, Nielsen KJ, Craik DJ, Loughnan ML, Adams DA, Sharpe IA, Luchian T, Adams DJ, Bond T, Thomas L et al.. (2000)
Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes. J Biol Chem, 275 (45): 35335-44. [PMID:10938268] |
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3. McDonough SI, Swartz KJ, Mintz IM, Boland LM, Bean BP. (1996)
Inhibition of calcium channels in rat central and peripheral neurons by omega-conotoxin MVIIC. J Neurosci, 16 (8): 2612-23. [PMID:8786437] |
