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Synonyms: ω-phonetoxin-2A | Neurotoxin Tx3-4 | Omega-ctenitoxin-Pn3a | Phoneutriatoxin 3-4
Compound class:
Peptide or derivative
Comment: From Phoneutria nigriventer (Brazilian armed spider or Ctenus nigriventer)
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
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1. Cassola AC, Jaffe H, Fales HM, Afeche SC, Magnoli F, Cipolla-Neto J. (1998)
ω-Phonetoxin-IIA: a calcium channel blocker from the spider Phoneutria nigriventer. Pflugers Arch, 436 (4): 545-52. [PMID:9683727] |
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2. Dos Santos RG, Van Renterghem C, Martin-Moutot N, Mansuelle P, Cordeiro MN, Diniz CR, Mori Y, De Lima ME, Seagar M. (2002)
Phoneutria nigriventer omega-phonetoxin IIA blocks the Cav2 family of calcium channels and interacts with omega-conotoxin-binding sites. J Biol Chem, 277 (16): 13856-62. [PMID:11827974] |
