5-benzyloxytryptamine

Ligand id: 265

Name: 5-benzyloxytryptamine

Abbreviated name: 5-BT

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 51.04
Molecular weight 266.14
XLogP 3.97
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Boess FG, Monsma FJ, Carolo C, Meyer V, Rudler A, Zwingelstein C, Sleight AJ. (1997)
Functional and radioligand binding characterization of rat 5-HT6 receptors stably expressed in HEK293 cells.
Neuropharmacology36: 713-720. [PMID:9225298]
2. Boess FG, Monsma FJ, Sleight AJ. (1998)
Identification of residues in transmembrane regions III and VI that contribute to the ligand binding site of the serotonin 5-HT6 receptor.
J Neurochem71: 2169-2177. [PMID:9798944]
3. Monsma FJ, Shen Y, Ward RP, Hamblin MW, Sibley DR. (1993)
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
Mol Pharmacol43: 320-327. [PMID:7680751]