[3H]AD5075

Ligand id: 2702

Name: [3H]AD5075    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 126.96
Molecular weight 424.11
XLogP 4.15
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Berger J, Bailey P, Biswas C, Cullinan CA, Doebber TW, Hayes NS, Saperstein R, Smith RG, Leibowitz MD. (1996)
Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: binding and activation correlate with antidiabetic actions in db/db mice.
Endocrinology137 (10): 4189-95. [PMID:8828476]