asoprisnil

Ligand id: 2883

Name: asoprisnil

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 68.12
Molecular weight 449.26
XLogP 5.33
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Yudt MR, Russo LA, Berrodin TJ, Jelinsky SA, Ellis D, Cohen JC, Cooch N, Haglund E, Unwalla RJ, Fensome A et al.. (2011)
Discovery of a novel mechanism of steroid receptor antagonism: WAY-255348 modulates progesterone receptor cellular localization and promoter interactions.
Biochem. Pharmacol.82 (11): 1709-19. [PMID:21854761]