Ligand Id: 2901
Ligand name [3H]resolvin E1

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 13
Topological polar surface area 97.99
Molecular weight 350.21
XLogP 2.24
No. Lipinski's rules broken 1

Molecular properties generated using the CDK


Summary Biological activity References Structure Similar ligands Radio analogues
References
1. Arita, M., Bianchini, F., Aliberti, J., Sher, A., Chiang, N., Hong, S., Yang, R., Petasis, N. A. and Serhan, C. N. (2005)
Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1.
J Exp Med201: 713-722. [PMID:15753205]
2. Arita, M; Ohira, T; Sun, YP; Elangovan, S; Chiang, N; Serhan, CN. (2007)
Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation.
J. Immunol.178 (6): 3912-7. [PMID:17339491]