Ligand Id: 2911
Ligand name farnesyl monophosphate

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 76.57
Molecular weight 302.16
XLogP 3.12
No. Lipinski's rules broken 0

Molecular properties generated using the CDK


Summary Biological activity References Structure Similar ligands
References
1. Williams, JR; Khandoga, AL; Goyal, P; Fells, JI; Perygin, DH; Siess, W; Parrill, AL; Tigyi, G; Fujiwara, Y. (2009)
Unique ligand selectivity of the GPR92/LPA5 lysophosphatidate receptor indicates role in human platelet activation.
J. Biol. Chem.284 (25): 17304-19. [PMID:19366702]
2. Liliom, K; Tsukahara, T; Tsukahara, R; Zelman-Femiak, M; Swiezewska, E; Tigyi, G. (2006)
Farnesyl phosphates are endogenous ligands of lysophosphatidic acid receptors: inhibition of LPA GPCR and activation of PPARs.
Biochim. Biophys. Acta1761 (12): 1506-14. [PMID:17092771]