compound 18 [PMID: 8426367]

Ligand id: 2961

Name: compound 18 [PMID: 8426367]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 37.3
Molecular weight 456.4
XLogP 10.4
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Frye LL, Cusack KP, Leonard DA. (1993)
32-Methyl-32-oxylanosterols: dual-action inhibitors of cholesterol biosynthesis.
J. Med. Chem.36 (3): 410-6. [PMID:8426367]