compound 29 [PMID: 2296027]

Ligand id: 2964

Name: compound 29 [PMID: 2296027]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 64.35
Molecular weight 436.22
XLogP 6.34
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Sliskovic DR, Roth BD, Wilson MW, Hoefle ML, Newton RS. (1990)
Inhibitors of cholesterol biosynthesis. 2. 1,3,5-trisubstituted [2-(tetrahydro-4-hydroxy-2-oxopyran-6-yl)ethyl]pyrazoles.
J. Med. Chem.33 (1): 31-8. [PMID:2296027]