compound 4rr [PMID: 1656041]

Ligand id: 2967

Name: compound 4rr [PMID: 1656041]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 55.76
Molecular weight 380.18
XLogP 5.15
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Jendralla H, Granzer E, von Kerekjarto B, Krause R, Schacht U, Baader E, Bartmann W, Beck G, Bergmann A, Kesseler K. (1991)
Synthesis and biological activity of new HMG-CoA reductase inhibitors. 3. Lactones of 6-phenoxy-3,5-dihydroxyhexanoic acids.
J. Med. Chem.34 (10): 2962-83. [PMID:1656041]