compound 4p [PMID: 1895299]

Ligand id: 3019

Name: compound 4p [PMID: 1895299]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 123.19
Molecular weight 509.18
XLogP 6.4
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Robl JA, Duncan LA, Pluscec J, Karanewsky DS, Gordon EM, Ciosek CP, Rich LC, Dehmel VC, Slusarchyk DA, Harrity TW. (1991)
Phosphorus-containing inhibitors of HMG-CoA reductase. 2. Synthesis and biological activities of a series of substituted pyridines containing a hydroxyphosphinyl moiety.
J. Med. Chem., 34 (9): 2804-15. [PMID:1895299]