compound 21 [PMID: 19191557]

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Ligands
compound 21 [PMID: 19191557]

Ligand id: 3119

Name: compound 21 [PMID: 19191557]

Structure and Physico-chemical Properties

2D Structure

Calculated Physico-chemical Properties
Hydrogen bond acceptors	6
Hydrogen bond donors	0
Rotatable bonds	8
Topological polar surface area	147.81
Molecular weight	401.03
XLogP	2.71
No. Lipinski's rules broken	0

Molecular properties generated using the CDK

Summary
Biological activity
References
Structure
Similar ligands

References
1. Song Y, Lin FY, Yin F, Hensler M, Rodrígues Poveda CA, Mukkamala D, Cao R, Wang H, Morita CT, González Pacanowska D et al.. (2009) Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus. J. Med. Chem., 52 (4): 976-88. [PMID:19191557]

References

1. Song Y, Lin FY, Yin F, Hensler M, Rodrígues Poveda CA, Mukkamala D, Cao R, Wang H, Morita CT, González Pacanowska D et al.. (2009)
Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus.
J. Med. Chem., 52 (4): 976-88. [PMID:19191557]