ipratropium

Ligand id: 325

Name: ipratropium

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 46.53
Molecular weight 332.22
XLogP 4.23
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Dowling MR, Charlton SJ. (2006)
Quantifying the association and dissociation rates of unlabelled antagonists at the muscarinic M(3) receptor.
Br J Pharmacol148: 927-937. [PMID:16847442]
2. Hirose H, Aoki I, Kimura T, Fujikawa T, Numazawa T, Sasaki K, Sato A, Hasegawa T, Nishikibe M, Mitsuya M, Ohtake N, Mase T, Noguchi K. (2001)
Pharmacological properties of (2R)-N-[1-(6-aminopyridin-2-ylmethyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide: a novel mucarinic antagonist with M(2)-sparing antagonistic activity.
J Pharmacol Exp Ther297: 790-797. [PMID:11303071]