BAY 60-6583

Ligand id: 3289

Name: BAY 60-6583

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 164.11
Molecular weight 379.11
XLogP 1.18
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Eckle T, Krahn T, Grenz A, K√∂hler D, Mittelbronn M, Ledent C, Jacobson MA, Osswald H, Thompson LF, Unertl K et al.. (2007)
Cardioprotection by ecto-5'-nucleotidase (CD73) and A2B adenosine receptors.
Circulation115 (12): 1581-90. [PMID:17353435]
2. Kuno A, Critz SD, Cui L, Solodushko V, Yang XM, Krahn T, Albrecht B, Philipp S, Cohen MV, Downey JM. (2007)
Protein kinase C protects preconditioned rabbit hearts by increasing sensitivity of adenosine A2b-dependent signaling during early reperfusion.
J. Mol. Cell. Cardiol.43 (3): 262-71. [PMID:17632123]