CDDO-Me

Ligand id: 3443

Name: CDDO-Me

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 84.23
Molecular weight 505.32
XLogP 6.62
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Wang Y, Porter WW, Suh N, Honda T, Gribble GW, Leesnitzer LM, Plunket KD, Mangelsdorf DJ, Blanchard SG, Willson TM, Sporn MB. (2000)
A synthetic triterpenoid, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator-activated receptor gamma.
Mol. Endocrinol.14 (10): 1550-6. [PMID:11043571]