antalarmin

Ligand id: 3489

Name: antalarmin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 33.95
Molecular weight 378.28
XLogP 6.75
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Webster EL, Lewis DB, Torpy DJ, Zachman EK, Rice KC, Chrousos GP. (1996)
In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation.
Endocrinology137 (12): 5747-50. [PMID:8940412]