[125I]relaxin-3-B/INSL5 A chimera   Click here for help

GtoPdb Ligand ID: 3789

Synonyms: [125I]H3-B/INSL5 A chimera
 Ligand is labelled  Ligand is radioactive
Compound class: Peptide or derivative
Comment: Synthetic chimeric analogue of human relaxin-3 and human INSL5. The B chain of human relaxin-3 is radiolabelled (using 125 at tyrosine 5) and forms a heteromer with the A chain of human INSL5. For details of the amino acid sequences of the subunits, see the ligand entries relaxin-3 (B chain) and INSL5 (A chain).
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
1. Liu C, Chen J, Kuei C, Sutton S, Nepomuceno D, Bonaventure P, Lovenberg TW. (2005)
Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7.
Mol Pharmacol, 67 (1): 231-40. [PMID:15465925]