sitaxsentan

Ligand id: 3950

Name: sitaxsentan

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 144.35
Molecular weight 454.01
XLogP 2.76
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Wu C, Chan MF, Stavros F, Raju B, Okun I, Mong S, Keller KM, Brock T, Kogan TP, Dixon RA. (1997)
Discovery of TBC11251, a potent, long acting, orally active endothelin receptor-A selective antagonist.
J. Med. Chem.40 (11): 1690-7. [PMID:9171878]