A-582941

Ligand id: 3995

Name: A-582941

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 32.26
Molecular weight 280.17
XLogP 3.91
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Bitner RS, Bunnelle WH, Anderson DJ, Briggs CA, Buccafusco J, Curzon P, Decker MW, Frost JM, Gronlien JH, Gubbins E et al.. (2007)
Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways.
J. Neurosci.27 (39): 10578-87. [PMID:17898229]