EMPA

Ligand id: 4037

Name: EMPA

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 10
Topological polar surface area 101.08
Molecular weight 454.17
XLogP 3.44
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Malherbe P, Borroni E, Gobbi L, Knust H, Nettekoven M, Pinard E, Roche O, Rogers-Evans M, Wettstein JG, Moreau JL. (2009)
Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX(2) receptor.
Br. J. Pharmacol.156 (8): 1326-41. [PMID:19751316]