atopaxar

Ligand id: 4048

Name: atopaxar

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 84.32
Molecular weight 527.28
XLogP 4.88
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Kogushi M, Matsuoka T, Kawata T, Kuramochi H, Kawaguchi S, Murakami K, Hiyoshi H, Suzuki S, Kawahara T, Kajiwara A et al.. (2011)
The novel and orally active thrombin receptor antagonist E5555 (Atopaxar) inhibits arterial thrombosis without affecting bleeding time in guinea pigs.
Eur. J. Pharmacol.657 (1-3): 131-7. [PMID:21300059]