flunitrazepam

Ligand id: 4193

Name: flunitrazepam

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 75.81
Molecular weight 313.09
XLogP 3.18
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Hadingham KL, Garrett EM, Wafford KA, Bain C, Heavens RP, Sirinathsinghji DJ, Whiting PJ. (1996)
Cloning of cDNAs encoding the human gamma-aminobutyric acid type A receptor alpha 6 subunit and characterization of the pharmacology of alpha 6-containing receptors.
Mol. Pharmacol.49 (2): 253-9. [PMID:8632757]
2. Krishek BJ, Moss SJ, Smart TG. (1998)
Interaction of H+ and Zn2+ on recombinant and native rat neuronal GABAA receptors.
J. Physiol. (Lond.)507 ( Pt 3): 639-52. [PMID:9508826]