Synonyms: VRT 532 | VRT532
Compound class:
Synthetic organic
Comment: The structure of this compound is drawn from the article which describes its discovery [2]. This compound is represented in PubChem by the alternative tautomer CID 5405906.
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References |
1. Pasyk S, Li C, Ramjeesingh M, Bear CE. (2009)
Direct interaction of a small-molecule modulator with G551D-CFTR, a cystic fibrosis-causing mutation associated with severe disease. Biochem J, 418 (1): 185-90. [PMID:18945216] |
2. Van Goor F, Straley KS, Cao D, González J, Hadida S, Hazlewood A, Joubran J, Knapp T, Makings LR, Miller M et al.. (2006)
Rescue of DeltaF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules. Am J Physiol Lung Cell Mol Physiol, 290 (6): L1117-30. [PMID:16443646] |