tiagabine

Ligand id: 4818

Name: tiagabine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 97.02
Molecular weight 375.13
XLogP 4.01
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Borden LA, Murali Dhar TG, Smith KE, Weinshank RL, Branchek TA, Gluchowski C. (1994)
Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1.
Eur. J. Pharmacol.269 (2): 219-24. [PMID:7851497]