valacyclovir

Ligand id: 4824

Name: valacyclovir

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 4
Rotatable bonds 8
Topological polar surface area 146.52
Molecular weight 325.16
XLogP -1.01
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Bhardwaj RK, Herrera-Ruiz D, Eltoukhy N, Saad M, Knipp GT. (2006)
The functional evaluation of human peptide/histidine transporter 1 (hPHT1) in transiently transfected COS-7 cells.
Eur J Pharm Sci27 (5): 533-42. [PMID:16289537]
2. Ganapathy ME, Huang W, Wang H, Ganapathy V, Leibach FH. (1998)
Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2.
Biochem. Biophys. Res. Commun.246 (2): 470-5. [PMID:9610386]