tetrabenazine

Ligand id: 4834

Name: tetrabenazine

Abbreviated name: TBZ

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 38.77
Molecular weight 317.2
XLogP 2.69
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Erickson JD, Schafer MK, Bonner TI, Eiden LE, Weihe E. (1996)
Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter.
Proc. Natl. Acad. Sci. U.S.A.93 (10): 5166-71. [PMID:8643547]
2. Jankovic J. (2016)
Dopamine depleters in the treatment of hyperkinetic movement disorders.
Expert Opin Pharmacother17 (18): 2461-2470. [PMID:27819145]