phenylephrine

Ligand id: 485

Name: phenylephrine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 3
Rotatable bonds 3
Topological polar surface area 52.49
Molecular weight 167.09
XLogP 0.46
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Ford APDW, Daniels DV, Chang DJ, Gever JR, Jasper JR, Lesnick JD, Clarke DE. (1997)
Pharmacological pleiotropism of the human recombinant α1A-adrenoceptor: implications for α1-adrenoceptor classification.
Br. J. Pharmacol.121: 1127-1135. [PMID:9249248]
2. Minneman KP, Theroux TL, Hollinger S, Han C, Esbenshade TA. (1994)
Selectivity of agonists for cloned α1-adrenergic receptor subtypes.
Mol. Pharmacol.46: 929-936. [PMID:7969082]
3. Taniguchi T, Inagaki R, Murata S, Akiba I, Muramatsu I. (1999)
Microphysiometric analysis of human alpha1a-adrenoceptor expressed in Chinese hamster ovary cells.
Br J Pharmacol127: 962-968. [PMID:10433504]