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Abbreviated name: Gas6
Synonyms: AXL receptor tyrosine kinase ligand
Compound class:
Endogenous peptide in human, mouse or rat
Comment: GAS6 is the sole ligand for AXL receptor tytrosine kinase. Because of AXL's roles in cancer, fibrosis and viral infection, GAS6 has emerged as an attractive target for drug development.
Species: Human
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| References |
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1. Nagata K, Ohashi K, Nakano T, Arita H, Zong C, Hanafusa H, Mizuno K. (1996)
Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases. J Biol Chem, 271 (47): 30022-7. [PMID:8939948] |
