rizatriptan

Ligand id: 51

Name: rizatriptan

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 49.74
Molecular weight 269.16
XLogP 1.35
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Napier C, Stewart M, Melrose H, Hopkins B, McHarg A, Wallis R. (1999)
Characterisation of the 5-HT receptor binding profile of eletriptan and kinetics of [3H]eletriptan binding at human 5-HT1B and 5-HT1D receptors.
Eur J Pharmacol368: 259-268. [PMID:10193663]
2. Wainscott DB, Krushinski JH, Audia JE, Schaus JM, Zgombick JM, Lucaites VL, Nelson DL. (2005)
[3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties.
Naunyn Schmiedebergs Arch Pharmacol371: 169-177. [PMID:15900510]