Synonyms: 4-chlorophenylalanine | p-Chlorophenylalanine | para-chlorophenylalanine | PCPA
Compound class:
Synthetic organic
Comment: A synthetic amino acid which covalently binds to tryptophan hydroxylase to cause depletion of serotonin in the brain [1].
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References |
1. Datla KP, Curzon G. (1996)
Effect of p-chlorophenylalanine at moderate dosage on 5-HT and 5-HIAA concentrations in brain regions of control and p-chloroamphetamine treated rats. Neuropharmacology, 35 (3): 315-20. [PMID:8783206] |
2. Koyuncuoğlu H, Eroğlu L, Güngör M. (1975)
The effects of DL-p-chlorophenylalanine and DL-alpha-methyl-p-tyrosine on the brain catecholamine, serotonin and free amino acid contents in rat. Psychopharmacologia, 45 (2): 163-6. [PMID:129787] |