sulindac

Ligand id: 5425

Name: sulindac

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 73.58
Molecular weight 356.09
XLogP 4.26
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Rocca J, Manin S, Hulin A, Aissat A, Verbecq-Morlot W, Prulière-Escabasse V, Wohlhuter-Haddad A, Epaud R, Fanen P, Tarze A. (2016)
New use for an old drug: COX-independent anti-inflammatory effects of sulindac in models of cystic fibrosis.
Br. J. Pharmacol.173 (11): 1728-41. [PMID:26894321]