compound 8g [PMID: 21444206]

Ligand id: 5739

Name: compound 8g [PMID: 21444206]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 0
Rotatable bonds 7
Topological polar surface area 140.96
Molecular weight 507.14
XLogP 2.9
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Semple G, Ren A, Fioravanti B, Pereira G, Calderon I, Choi K, Xiong Y, Shin YJ, Gharbaoui T, Sage CR et al.. (2011)
Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.
Bioorg. Med. Chem. Lett.21 (10): 3134-41. [PMID:21444206]