compound 1 [PMID: 21273063]

Ligand id: 5745

Name: compound 1 [PMID: 21273063]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 45.67
Molecular weight 345.24
XLogP 3.59
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Szewczyk JW, Acton J, Adams AD, Chicchi G, Freeman S, Howard AD, Huang Y, Li C, Meinke PT, Mosely R et al.. (2011)
Design of potent and selective GPR119 agonists for type II diabetes.
Bioorg. Med. Chem. Lett.21 (9): 2665-9. [PMID:21273063]