treprostinil

Ligand id: 5820

Name: treprostinil

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 10
Topological polar surface area 86.99
Molecular weight 390.24
XLogP 4.74
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Whittle BJ, Silverstein AM, Mottola DM, Clapp LH. (2012)
Binding and activity of the prostacyclin receptor (IP) agonists, treprostinil and iloprost, at human prostanoid receptors: treprostinil is a potent DP1 and EP2 agonist.
Biochem. Pharmacol.84 (1): 68-75. [PMID:22480736]