IL-17F

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Ligands
IL-17F (Human)

GtoPdb Ligand ID: 5873

Synonyms: cytokine ML-1 | Interleukin-17F

Compound class: Endogenous peptide in human, mouse or rat

Comment: Forms homodimeric ligand IL-17F and heterodimer IL-17A/IL-17F with IL-17A.

Species: Human

References
1. Adams R, Popplewell AG, Rapecki SE. (2008) Antibody molecules which bind il-17a and il-17f. Patent number: WO2008047134. Assignee: Ucb Pharma S.A.. Priority date: 18/10/2006. Publication date: 24/04/2008.
2. Bruniquel D, Chavalet L, Chvatchko Y, Kilkman JA, Leger O, Proudfoot AEI, Rommelaere H, Saunders MJS, Union A, Vicari A. (2012) Amino acid sequences directed against il-17a, il-17f and/or il17-a/f and polypeptides comprising the same. Patent number: WO2012156219A1. Assignee: Ablynx Nv, Merck Patent Gmbh. Priority date: 05/05/2011. Publication date: 22/11/2012.
3. Ganesan R, Rasool M. (2017) Interleukin 17 regulates SHP-2 and IL-17RA/STAT-3 dependent Cyr61, IL-23 and GM-CSF expression and RANKL mediated osteoclastogenesis by fibroblast-like synoviocytes in rheumatoid arthritis. Mol Immunol, 91: 134-144. [PMID:28898718]

References

1. Adams R, Popplewell AG, Rapecki SE. (2008)
Antibody molecules which bind il-17a and il-17f.
Patent number: WO2008047134. Assignee: Ucb Pharma S.A.. Priority date: 18/10/2006. Publication date: 24/04/2008.

2. Bruniquel D, Chavalet L, Chvatchko Y, Kilkman JA, Leger O, Proudfoot AEI, Rommelaere H, Saunders MJS, Union A, Vicari A. (2012)
Amino acid sequences directed against il-17a, il-17f and/or il17-a/f and polypeptides comprising the same.
Patent number: WO2012156219A1. Assignee: Ablynx Nv, Merck Patent Gmbh. Priority date: 05/05/2011. Publication date: 22/11/2012.

3. Ganesan R, Rasool M. (2017)
Interleukin 17 regulates SHP-2 and IL-17RA/STAT-3 dependent Cyr61, IL-23 and GM-CSF expression and RANKL mediated osteoclastogenesis by fibroblast-like synoviocytes in rheumatoid arthritis.
Mol Immunol, 91: 134-144. [PMID:28898718]