Synonyms: K 12148 | K12.148 | U-83860
Compound class:
Synthetic organic
Comment: Lifibrol is a model compound being investigated in the development of novel pharmacotherapies for dyslipidaemia [1]. The compoound appears to be a cholesterol synthesis inhibitor.
The INN document for lifibrol specifies that it is a racemic mixture of two enatiomers. We do not specify stereochemistry in our structure therefore this entry represents the mixture. |
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References |
1. Berthold HK, Sudhop T, von Bergmann K, Gouni-Berthold I. (2010)
Lifibrol as a model compound for a novel lipid-lowering mechanism of action. J Cardiovasc Pharmacol Ther, 15 (4): 364-72. [PMID:20693157] |
2. Locker PK, Jungbluth GL, Francom SF, Hughes Jr GS. (1995)
Lifibrol: a novel lipid-lowering drug for the therapy of hypercholesterolemia. Lifibrol Study Group. Clin Pharmacol Ther, 57 (1): 73-88. [PMID:7828385] |