temsirolimus

Ligand id: 5892

Name: temsirolimus

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: temsirolimus

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 17
Hydrogen bond donors 4
Rotatable bonds 11
Topological polar surface area 241.96
Molecular weight 1029.6
XLogP 3.54
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

References
1. Kong F, Zhu T, Yu K, Pagano TG, Desai P, Radebaugh G, Fawzi M. (2011)
Isolation and structure of homotemsirolimuses A, B, and C.
J. Nat. Prod.74 (4): 547-53. [PMID:21438579]