compound 14a [PMID: 18812259]

Ligand id: 6254

Name: compound 14a [PMID: 18812259]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 43.18
Molecular weight 382.16
XLogP 3.34
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Zhang L, Rogers BN, Duplantier AJ, McHardy SF, Efremov I, Berke H, Qian W, Zhang AQ, Maklad N, Candler J et al.. (2008)
3-(Imidazolyl methyl)-3-aza-bicyclo[3.1.0]hexan-6-yl)methyl ethers: a novel series of mGluR2 positive allosteric modulators.
Bioorg. Med. Chem. Lett.18 (20): 5493-6. [PMID:18812259]