4-APPES

Ligand id: 6258

Name: 4-APPES

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 110.97
Molecular weight 411.13
XLogP 3.62
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Johnson MP, Barda D, Britton TC, Emkey R, Hornback WJ, Jagdmann GE, McKinzie DL, Nisenbaum ES, Tizzano JP, Schoepp DD. (2005)
Metabotropic glutamate 2 receptor potentiators: receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s).
Psychopharmacology (Berl).179: 271- 283. [PMID:15717213]