compound 23c [PMID: 17929793]

Ligand id: 6345

Name: compound 23c [PMID: 17929793]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 91.93
Molecular weight 366.08
XLogP 1.44
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Wu WL, Burnett DA, Domalski M, Greenlee WJ, Li C, Bertorelli R, Fredduzzi S, Lozza G, Veltri A, Reggiani A. (2007)
Discovery of orally efficacious tetracyclic metabotropic glutamate receptor 1 (mGluR1) antagonists for the treatment of chronic pain.
J. Med. Chem., 50 (23): 5550-3. [PMID:17929793]