compound 26 [PMID: 16439120]

Ligand id: 6372

Name: compound 26 [PMID: 16439120]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 58.8
Molecular weight 259.05
XLogP 2.66
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. B├╝ttelmann B, Peters JU, Ceccarelli S, Kolczewski S, Vieira E, Prinssen EP, Spooren W, Schuler F, Huwyler J, Porter RH et al.. (2006)
Arylmethoxypyridines as novel, potent and orally active mGlu5 receptor antagonists.
Bioorg. Med. Chem. Lett., 16 (7): 1892-7. [PMID:16439120]