Br-5MPEPy

Ligand id: 6397

Name: Br-5MPEPy

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 0
Topological polar surface area 25.78
Molecular weight 271.99
XLogP 3.56
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Rodriguez AL, Nong Y, Sekaran NK, Alagille D, Tamagnan GD, Conn PJ. (2005)
A close structural analog of 2-methyl-6-(phenylethynyl)-pyridine acts as a neutral allosteric site ligand on metabotropic glutamate receptor subtype 5 and blocks the effects of multiple allosteric modulators.
Mol Pharmacol68: 1793-1802. [PMID:16155210]